Passive targeted temperature management in the intensive care of severe neonatal hypoxic-ischemic encefalopathy
نویسنده
چکیده
Surkov. Temperature and neonatal hypoxic-ischemic encefalopathy 1 Key points Therapeutic hypothermia or targeted temperature management has been shown to improve outcome after perinatal asphyxia in large clinical trials. Controlled cooling has become the standard of care for newborns with hypoxicischemic encephalopathy but preference of its method still remains controversial. The efficacy and safety of passive “non-heating” targeted temperature management as well as feasibility and reliability of non-invasive transfontanel Doppler evaluation of cerebral blood flow and perfusion pressure after undergoing severe hypoxia-ischemia in term infants were obtained during the study. Passive targeted temperature management in the intensive care of severe neonatal hypoxic-ischemic encefalopathy
منابع مشابه
Passive hypothermia (≥35 - <36°C) during transport of newborns with hypoxic-ischaemic encephalopathy
BACKGROUND Hypothermia initiated in the first six hours of life in term infants with hypoxic ischemic encephalopathy reduces the risk of death and severe neurological sequelae. Our study's principal objective was to evaluate transport predictors potentially influencing arrival in NICU (Neonatal Intensive Care Unit) at a temperature ≥35-<36°C. METHODOLOGY/PRINCIPAL FINDINGS A multi-centric, pr...
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Neonatal encephalopathy after perinatal hypoxic-ischemic insult is a major contributor to global child mortality and morbidity. Brain injury in term infants in response to hypoxic-ischemic insult is a complex process evolving over hours to days, which provides a unique window of opportunity for neuroprotective treatment interventions. Advances in neuroimaging, brain monitoring techniques, and t...
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Targeted temperature management (TTM) shows the most promising neuroprotective therapy against hypoxic/ischemic encephalopathy (HIE). In addition, TTM is also useful for treatment of elevated intracranial pressure (ICP). HIE and elevated ICP are common catastrophic conditions in patients admitted in Neurologic intensive care unit (ICU). The most common cause of HIE is cardiac arrest. Randomized...
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